Canine
DKA, ketoacidotic diabetes mellitus (KADM)
Dogs and cats.
Diabetic ketoacidosis, or DKA, is one of the most serious metabolic disorders seen in both human and veterinary medicine. A severe complication of diabetes mellitus, DKA is characterized by an elevated concentration of blood sugar, the presence of substances called ketones in the urine, and reduced concentrations of bicarbonate in the blood. Some dogs with DKA will be affected mildly, but the majority will be seriously ill and may have severe complications such as neurological problems due to brain swelling, acute kidney failure, pancreatitis, and anemia. DKA will lead to death in many cases, but aggressive diagnostics and treatment can be life saving.
DKA often develops in dogs with diabetes that had previously been unrecognized or untreated. Thus, it is essential to identify diabetes mellitus or the development of additional symptoms in a dog that is known to be diabetic to prevent DKA from occurring.