Cause
Most cases of chronic kidney failure are idiopathic -- meaning that they have no specific cause. Older cats tend to develop the disease because there is a normal decline in kidney function with aging. There are certain medical conditions that do tend to lead to chronic kidney failure, which include: inherited and congenital kidney disease, toxins of the kidneys, high blood calcium, and a condition called glomerulonephritis, in which the internal structures of the kidney become inflamed. Other diseases associated with kidney failure include kidney infection, polycystic kidney disease, kidney stones, feline infectious peritonitis, chronic urinary obstruction, and cancer. In addition, a condition called renal amyloidosis, in which proteins are distributed within the kidney, may lead to the illness.