Distemper Virus, Canine - contd.

ClinicalSigns
Anorexia; depression; listlessness; fever; upper respiratory tract infections; a thick, yellow discharge from the nose and eyes; coughing; dyspnea; vomiting; and diarrhea. Hyperkeratosis of the nose and pads of the paws can occur. In young dogs, enamel hypoplasia of the teeth is seen in neonatal infections. Neurological disease can occur and often includes seizures, paraparesis or tetraparesis, hyperesthesia, myoclonus, and death.

Symptoms
Decreased appetite and weight loss; depression; listlessness; fever; upper respiratory tract infections; a thick, yellow discharge coming from the nose and eyes; coughing; difficulty breathing; vomiting; and diarrhea. Hardening of the nose and pads of the paws can occur, and with younger dogs, damage to the teeth may result. Neurological disease signifies the most serious stage of the illness: seizures, paralysis of two or four legs, and involuntary twitching of the muscles are common nervous system disorders resulting from distemper. The disease can be deadly.