Pyometra, Canine - contd.
E. coli and other bacteria tend to overgrow in a hormone-sensitized uterus.
Pyometra may be a natural complication of degenerative and inflammatory changes that attend cystic endometrial hyperplasia in the aging intact female. In younger dogs, the problem is most often linked to progesterone administration for estrus synchronization or to estrogen given to aid in pregnancy prevention after inadvertent mating.
