Blastomycosis - contd.
The prognosis for treatment is guarded. Animals with severe respiratory or central nervous system signs have the poorest prognoses. With severe disease, animals often succumb during the first week of treatment, due to the inflammatory response that occurs as the organism is killed. If the animal does respond to treatment, the prognosis is more favorable; however, recurrence is seen in about 20 percent of cases, generally occurring within the first six months. A full course of therapy must be reinitiated in cases of relapse. Rarely, animals require lifelong treatment to control the disease.